RT Book, Section A1 Stringer, Janet L. SR Print(0) ID 1187633187 T1 Drug Metabolism and Renal Elimination T2 Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, 6e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264264841 LK accessmedicine.mhmedical.com/content.aspx?aid=1187633187 RD 2024/04/25 AB The liver is a major site for drug metabolism. The goal of metabolism is to produce metabolites that are polar or charged and can be eliminated by the kidney. Lipidsoluble agents are metabolized by the liver using two general sets of reactions, called phase I and phase II.