RT Book, Section A1 Laposata, Michael A1 McCaffrey, Peter SR Print(0) ID 1187001183 T1 Methods in Clinical Hematology T2 Clinical Laboratory Methods: Atlas of Commonly Performed Tests YR 2022 FD 2022 PB McGraw Hill, LLC PP New York, NY SN 9781260470284 LK accessmedicine.mhmedical.com/content.aspx?aid=1187001183 RD 2024/04/19 AB In most automated instruments that count cells in the blood, the red blood cells, the white blood cells, and the platelets are counted by an electrical impedance method. In addition, hemoglobin is measured directly from the whole blood specimen after lysis of the red blood cells. There are many other parameters in an automated blood cell count, which are calculated, based upon the data obtained from the direct cell counts and the hemoglobin value. Calculated parameters include the hematocrit, red blood cell count, the mean corpuscular volume (MCV), the mean corpuscular hemoglobin (MCH), the mean corpuscular hemoglobin concentration (MCHC) of red blood cells, and the mean platelet volume (MPV). The white blood cell differential count is obtained after lysis of erythrocytes, using flow cytometric technology to identify size, shape, and granularity of the cells which permits identification of the individual white blood cell populations.