RT Book, Section A1 Paulsen, Douglas F. SR Print(0) ID 1186643545 T1 Methods of Study T2 Histology and Cell Biology: Examination & Board Review, 6e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269921 LK accessmedicine.mhmedical.com/content.aspx?aid=1186643545 RD 2024/03/29 AB OBJECTIVESThis chapter should help the student to:Understand the mathematical relationships among the units of measure used for histologic specimens.Name the instruments and techniques used to prepare and study histologic specimens; know the attendant advantages and limitations of each.Describe and compare the basic steps in preparing specimens for light and electron microscopy.Select appropriate methods to reveal specific microscopic features and substances in cells and tissues.Describe the basic principles of histochemistry.List examples of the substances of biologic interest that can be localized by histochemical techniques.Name the classes of histochemical techniques and describe the advantages and limitations of each.Name and describe methods appropriate for isolating and studying specific cells and tissues from intact organisms.Name and describe methods appropriate for isolating and identifying proteins and nucleic acid sequences from cells and tissues.