RT Book, Section A1 Pyeritz, Reed E. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184181701 T1 Neoplasia: Cytogenomic & DNA Analysis T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184181701 RD 2024/04/20 AB Studies of both chromosomes and nucleic acids support Boveri's 1914 hypothesis that cancer is caused by a change in genetic material at the cellular level. Three classes of genes can be involved in neoplastic transformation.