RT Book, Section
A1 Smollin, Craig
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1184179551
T1 Calcium Channel Blockers Overdose
T2 Current Medical Diagnosis & Treatment 2022
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269389
LK accessmedicine.mhmedical.com/content.aspx?aid=1184179551
RD 2024/04/25
AB In  therapeutic  doses,  nifedipine,  nicardipine,  amlodipine,  felodipine,  isradipine,  nisoldipine,  and  nimodipine  act  mainly  on  blood  vessels,  while  verapamil  and  diltiazem  act  mainly  on  cardiac  contractility  and  conduction.  However,  these  selective  effects  can  be  lost  after  acute  overdose.  Patients  may  present  with  bradycardia,  atrioventricular  (AV)  nodal  block,  hypotension,  or  a  combination  of  these  effects.  Hyperglycemia  is  common  due  to  blockade  of  insulin  release.  With  severe  poisoning,  cardiac  arrest  may  occur.