RT Book, Section
A1 Smollin, Craig
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1184179272
T1 Poisoning or Overdose–Related Coma
T2 Current Medical Diagnosis & Treatment 2022
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269389
LK accessmedicine.mhmedical.com/content.aspx?aid=1184179272
RD 2024/04/25
AB Coma  is  commonly  associated  with  ingestion  of  large  doses  of  antihistamines  (eg,  diphenhydramine),  benzodiazepines  and  other  sedative-hypnotic  drugs,  ethanol,  opioids,  antipsychotic  drugs,  or  antidepressants.  The  most  common  cause  of  death  in  comatose  patients  is  respiratory  failure,  which  may  occur  abruptly.  Pulmonary  aspiration  of  gastric  contents  may  also  occur,  especially  in  victims  who  are  deeply  obtunded  or  convulsing.  Hypoxia  and  hypoventilation  may  cause  or  aggravate  hypotension,  arrhythmias,  and  seizures.  Thus,  protection  of  the  airway  and  assisted  ventilation  are  the  most  important  treatment  measures  for  any  poisoned  patient.