RT Book, Section A1 Rose, Stacey R. A1 Hamill, Richard J. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184175160 T1 Mycetoma (Eumycetoma & Actinomycetoma) T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184175160 RD 2024/03/28 AB Mycetoma is a chronic local, slowly progressive destructive infection that usually involves the foot; it begins in subcutaneous tissues, frequently after implantation of vegetative material into tissues during occupational activities. The infection then spreads to contiguous structures with sinus tracts and extruding grains. Eumycetoma (also known as maduromycosis) is the term used to describe mycetoma caused by true fungi. Actinomycotic mycetoma is caused by Actinomadura, Streptomyces, and Nocardia species. The disease begins as a papule, nodule, or abscess that over months to years progresses slowly to form multiple abscesses and sinus tracts ramifying deep into the tissue. Secondary bacterial infection may result in large open ulcers. Radiographs may show destructive changes in the underlying bone. Causative species can often be suggested by the color of the characteristic grains and hyphal size within the infected tissues but definitive diagnosis requires culture.