RT Book, Section
A1 Rosenthal, Philip J.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1184174250
T1 Clonorchiasis & Opisthorchiasis
T2 Current Medical Diagnosis & Treatment 2022
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269389
LK accessmedicine.mhmedical.com/content.aspx?aid=1184174250
RD 2024/04/24
AB Infection  by  Clonorchis  sinensis,  the  Chinese  liver  fluke,  is  endemic  in  areas  of  Japan,  Korea,  China,  Taiwan,  Southeast  Asia,  and  the  far  eastern  part  of  Russia.  An  estimated  15  million  people  are  infected  (13  million  in  China);  in  some  communities,  prevalence  can  reach  80%.  Opisthorchiasis  is  principally  caused  by  Opisthorchis  felineus  (regions  of  the  former  Soviet  Union)  or  Opisthorchis  viverrini  (Thailand,  Laos,  Vietnam).  Clonorchiasis  and  opisthorchiasis  are  clinically  indistinguishable.  Parasite  eggs  are  shed  into  water  in  human  or  animal  feces,  where  they  infect  snails,  which  release  cercariae,  which  infect  fish.  Human  infection  follows  ingestion  of  raw,  undercooked,  or  pickled  freshwater  fish  containing  metacercariae.  These  parasites  excyst  in  the  duodenum  and  ascend  into  the  biliary  tract,  where  they  mature  and  remain  for  many  years,  shedding  eggs  in  the  bile  (eFigure  35–19).