RT Book, Section A1 Philip, Susan S. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184172497 T1 Syphilis: Course & Prognosis T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184172497 RD 2024/04/19 AB The lesions associated with primary and secondary syphilis are self-limiting, even without treatment, and resolve with few or no residua. Ocular and otologic syphilis have been associated with permanent vision and hearing loss. Tertiary and congenital syphilis may be highly destructive and permanently disabling and may lead to death. While infection is almost never completely eradicated in the absence of treatment, most infections likely remain latent without sequelae, and only a small number of latent infections progress to further disease.