RT Book, Section
A1 Boslett, Bryn A.
A1 Bystritsky, Rachel
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1184171015
T1 Enterococcal Infections
T2 Current Medical Diagnosis & Treatment 2022
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269389
LK accessmedicine.mhmedical.com/content.aspx?aid=1184171015
RD 2024/04/19
AB Two  species,  Enterococcus  faecalis  and  Enterococcus  faecium,  are  responsible  for  most  human  enterococcal  infections.  Enterococci  cause  wound  infections,  urinary  tract  infections,  bacteremia,  and  endocarditis.  Infections  caused  by  penicillin-susceptible  strains  should  be  treated  with  ampicillin  2  g  every  4  hours  or  penicillin  3–4  million  units  every  4  hours;  if  the  patient  is  penicillin-allergic,  vancomycin  15  mg/kg  every  12  hours  intravenously  can  be  given.  If  the  patient  has  endocarditis  or  meningitis,  gentamicin  1  mg/kg  every  8  hours  intravenously  should  be  added  to  the  regimen  for  a  duration  of  2–3  weeks  in  order  to  achieve  the  bactericidal  activity  that  is  required  to  cure  these  infections.  In  cases  of  endocarditis,  ceftriaxone  2  g  every  12  hours  may  be  given  instead  of  gentamicin  in  combination  with  the  ampicillin.