RT Book, Section
A1 Blaha, Michael J.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1184162732
T1 Lipid Disorders: Clinical Presentations
T2 Current Medical Diagnosis & Treatment 2022
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269389
LK accessmedicine.mhmedical.com/content.aspx?aid=1184162732
RD 2024/04/25
AB Most  patients  with  high  cholesterol  levels  have  no  specific  symptoms  or  signs.  The  vast  majority  of  patients  with  lipid  abnormalities  are  detected  by  the  laboratory,  either  as  part  of  the  workup  of  a  patient  with  CVD  or  as  part  of  a  preventive  screening  strategy.  Extremely  high  levels  of  chylomicrons  or  VLDL  particles  (triglyceride  level  above  1000  mg/dL  or  10  mmol/L)  result  in  the  formation  of  eruptive  xanthomas  (Figure  28–1)  (red-yellow  papules,  especially  on  the  buttocks  [eFigure  28–2]).  High  LDL  concentrations  result  in  tendinous  xanthomas  on  certain  tendons  (Achilles,  patella,  back  of  the  hand  [eFigures  28–3,  28–4,  28–5]).  Such  xanthomas  usually  indicate  one  of  the  underlying  genetic  hyperlipidemias.  Lipemia  retinalis  (cream-colored  blood  vessels  in  the  fundus)  is  seen  with  extremely  high  triglyceride  levels  (above  2000  mg/dL  or  20  mmol/L).