RT Book, Section A1 Fitzgerald, Paul A. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184698115 T1 Male Hypogonadism T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184698115 RD 2024/04/18 AB Key Clinical Updates in Male HypogonadismAn oral preparation of testosterone undeconoate (Jatenzo) is available in capsules of 158 mg, 198 mg, and 237 mg and should be taken with food.Serum testosterone falls to low levels by 12 hours after an oral dose; dosing every 8 hours may produce more consistent serum testosterone levels.Testosterone replacement has not been considered to significantly increase the risk of thromboembolic events in most hypogonadal men.However, one large medical database study has found a correlation between testosterone therapy and thromboembolic events, particularly in men with a prior history of vascular events and in men being prescribed testosterone without proper documentation of hypogonadism.