RT Book, Section A1 Fitzgerald, Paul A. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184697561 T1 Metabolic Bone Disease T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184697561 RD 2024/04/18 AB The term "metabolic bone disease" refers to conditions producing diffuse reductions or increases in bone density that affect bone integrity. Conditions causing reduced bone density include osteopenia/osteoporosis and osteomalacia. Osteoporosis is characterized by reduction in both bone matrix and mineral, whereas in osteomalacia the bone matrix is intact but bone mineral is decreased. Conditions causing increased bone density are less common and include osteopetrosis, fluorosis, fibrous dysplasia, and Paget disease of bone. Metabolic bone diseases may cause bone pain and fractures.