RT Book, Section
A1 Douglas, Vanja C.
A1 Aminoff, Michael J.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1184185025
T1 Peripheral Neuropathies
T2 Current Medical Diagnosis & Treatment 2022
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269389
LK accessmedicine.mhmedical.com/content.aspx?aid=1184185025
RD 2024/04/18
AB Peripheral  neuropathies  can  be  categorized  on  the  basis  of  the  structure  primarily  affected.  The  predominant  pathologic  feature  may  be  axonal  degeneration  (axonal  or  neuronal  neuropathies)  or  paranodal  or  segmental  demyelination.  The  distinction  may  be  possible  on  the  basis  of  neurophysiologic  findings.  Motor  and  sensory  conduction  velocity  can  be  measured  in  accessible  segments  of  peripheral  nerves.  In  axonal  neuropathies,  conduction  velocity  is  normal  or  reduced  only  mildly  and  needle  electromyography  provides  evidence  of  denervation  in  affected  muscles.  In  demyelinating  neuropathies,  conduction  may  be  slowed  considerably  in  affected  fibers,  and  in  more  severe  cases,  conduction  is  blocked  completely,  without  accompanying  electromyographic  signs  of  denervation.