RT Book, Section
A1 Dirkx, Tonja C.
A1 Woodell, Tyler B.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1184183496
T1 Medullary Sponge Kidney
T2 Current Medical Diagnosis & Treatment 2022
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269389
LK accessmedicine.mhmedical.com/content.aspx?aid=1184183496
RD 2024/04/18
AB Medullary  sponge  kidney  is  believed  to  affect  less  than  1%  of  the  general  population.  Although  present  at  birth,  it  is  not  usually  diagnosed  until  the  fourth  or  fifth  decade.  It  is  thought  to  occur  due  to  disruption  of  the  ureteric  bud-metanephric  mesenchyme  interface,  often  resulting  from  autosomal  dominant  mutations  in  genes  responsible  for  urogenital  development.  Kidneys  have  a  marked  irregular  enlargement  of  the  medullary  and  interpapillary  collecting  ducts.  This  is  associated  with  medullary  cysts  that  are  diffuse,  giving  a  “Swiss  cheese”  appearance  in  these  regions.