RT Book, Section
A1 Dirkx, Tonja C.
A1 Woodell, Tyler B.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1184183209
T1 Glomerular Diseases
T2 Current Medical Diagnosis & Treatment 2022
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269389
LK accessmedicine.mhmedical.com/content.aspx?aid=1184183209
RD 2023/09/26
AB Glomerular  diseases  can  be  challenging  to  understand  clinically  because  the  glomerulus  is  a  histologically  complex  structure  (consisting  of  the  epithelial  cells  [podocytes],  basement  membrane,  capillary  endothelium,  and  mesangium).  The  following  are  examples  of  injuries  that  can  affect  any  or  all  of  the  constituents  of  the  glomerulus:  (1)  overwork  injury,  as  in  CKD;  (2)  an  inflammatory  process,  such  as  SLE;  (3)  a  podocyte  protein  mutation,  as  in  hereditary  focal  segmental  glomerulosclerosis  (FSGS);  or  (4)  a  deposition  disease,  as  in  diabetes  or  amyloidosis.  When  a  glomerular  disease  is  suspected,  a  kidney  biopsy  may  be  needed  to  clarify  the  etiology.