RT Book, Section
A1 Arora, Nayan
A1 Jefferson, J. Ashley
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1184182724
T1 Acid-Base Disorders
T2 Current Medical Diagnosis & Treatment 2022
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269389
LK accessmedicine.mhmedical.com/content.aspx?aid=1184182724
RD 2024/04/19
AB Acid-base  regulation  is  the  maintenance  of  normal  hydrogen  ion  concentration.  The  normal  plasma  hydrogen  ion  concentration  is  40  nmol/L,  which  corresponds  to  a  pH  of  7.4  (the  negative  log  of  its  concentration).  Any  decrease  in  blood  pH  represents  an  increase  in  hydrogen  ion  concentration  (acidemia),  while  an  increase  in  blood  pH  represents  a  decrease  in  hydrogen  ion  concentration  (alkalemia).  Bicarbonate  (HCO3–)  is  the  primary  acid  buffer  in  the  body  and  the  relationship  between  acid  and  base  behavior  in  the  body  is  shown  by  the  Henderson-Hasselbalch  equation  below.  Note  that  because  carbon  dioxide  is  primarily  measured  as  a  partial  pressure,  the  denominator  contains  a  conversion  factor.