RT Book, Section A1 Yazdany, Jinoos A1 Manno, Rebecca L. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184193464 T1 Ankylosing Spondylitis T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184193464 RD 2024/03/28 AB ESSENTIALS OF DIAGNOSISChronic low backache and stiffness in young adults, worst in the morning.Progressive limitation of back motion and chest expansion.Transient (50%) or persistent (25%) peripheral arthritis.Anterior uveitis in 20–25%.Diagnostic radiographic changes in sacroiliac joints.Negative serologic tests for rheumatoid factor and anti-CCP antibodies.HLA-B27 testing is most helpful when there is an intermediate probability of disease.