RT Book, Section
A1 Yazdany, Jinoos
A1 Manno, Rebecca L.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1184192979
T1 Crystal Deposition Arthritis
T2 Current Medical Diagnosis & Treatment 2022
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269389
LK accessmedicine.mhmedical.com/content.aspx?aid=1184192979
RD 2024/04/25
AB KEY  CLINICAL  UPDATES  IN  CRYSTAL  DEPOSITION  ARTHRITISIn  a  2020  randomized,  controlled  trial  in  patients  with  CKD  and  a  high  risk  of  its  progression,  urate-lowering  treatment  with  allopurinol  did  not  slow  the  decline  in  eGFR  when  compared  to  placebo.In  patients  with  concomitant  coronary  artery  disease,  long-term  colchicine  use  can  reduce  major  cardiovascular  events.Despite  initial  concern  that  febuxostat  was  associated  with  more  cardiovascular  events  than  allopurinol,  a  large,  randomized,  controlled  trial  in  2020  showed  that  the  two  drugs  have  similar  cardiovascular  safety.