RT Book, Section A1 Rogers, Vanessa L. A1 Roberts, Scott W. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184182333 T1 Gastrointestinal, Hepatic, & Biliary Disorders of Pregnancy T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184182333 RD 2024/04/25 AB Complications involving the gastrointestinal tract, liver, and gallbladder are common in pregnancy. Nausea and vomiting in the first trimester affect the majority of pregnant women to some degree (see Obstetric Complications of the First & Second Trimesters). Nausea and vomiting in the last half of pregnancy, however, are never normal; a thorough evaluation of such complaints is mandatory. Some of these conditions are incidental to pregnancy (eg, appendicitis), while others are related to the gravid state and tend to resolve with delivery (eg, acute fatty liver of pregnancy). Importantly, the myriad anatomic and physiologic changes associated with normal pregnancy must be considered when assessing for a disease state. Likewise, interpretation of laboratory studies must take into account the pregnancy-associated changes in hepatic protein production.