RT Book, Section
A1 Rogers, Vanessa L.
A1 Roberts, Scott W.
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1184181945
T1 Prevention of Rhesus Alloimmunization
T2 Current Medical Diagnosis & Treatment 2022
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269389
LK accessmedicine.mhmedical.com/content.aspx?aid=1184181945
RD 2024/04/19
AB The  antibody  anti-Rho(D)  causes  severe  hemolytic  disease  of  the  newborn.  About  15%  of  Whites  and  much  lower  proportions  of  Blacks  and  Asians  are  Rho(D)–negative.  If  an  Rho(D)–negative  woman  carries  an  Rho(D)–positive  fetus,  antibodies  against  Rho(D)  may  develop  in  the  mother  when  fetal  red  cells  enter  her  circulation  during  small  fetomaternal  bleeding  episodes  in  the  early  third  trimester  or  during  delivery,  abortion,  ectopic  pregnancy,  placental  abruption,  or  other  instances  of  antepartum  bleeding.  This  antibody,  once  produced,  remains  in  the  woman's  circulation  and  poses  the  threat  of  hemolytic  disease  for  subsequent  Rh-positive  fetuses.