RT Book, Section A1 Bashore, Thomas M. A1 Granger, Christopher B. A1 Jackson, Kevin P. A1 Patel, Manesh R. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184696467 T1 Diseases of the Pericardium: Anatomic & Physiologic Considerations T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184696467 RD 2024/04/18 AB The pericardium consists of two layers: the inner visceral layer, which is attached to the epicardium, and an outer parietal layer. About 50 mL of serous fluid is normally present and provides lubrication between the two layers. The pericardial reflection encompasses the heart and great vessels. The pericardium stabilizes the heart in anatomic position and reduces contact between the heart and the surrounding structures. It is composed of fibrous tissue, and although it will permit moderate changes in cardiac size, it cannot stretch rapidly enough to accommodate rapid dilation of the heart or accumulation of fluid without increasing intrapericardial (and, therefore, intracardiac) pressure.