RT Book, Section A1 Bashore, Thomas M. A1 Granger, Christopher B. A1 Jackson, Kevin P. A1 Patel, Manesh R. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184695075 T1 Ventricular Septal Defect T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184695075 RD 2024/04/16 AB ESSENTIALS OF DIAGNOSISA restrictive VSD is small and makes a louder murmur than an unrestricted one, often with an accompanying thrill. The higher the gradient across the septum, the smaller the left-to-right shunt.Small defects may be asymptomatic.Larger defects result in pulmonary hypertension (Eisenmenger physiology) if not repaired or if the pulmonary circuit is not protected by RV outflow tract obstruction.Echocardiography/Doppler is diagnostic.