RT Book, Section
A1 Fitzpatrick, Meghan E.
A1 Prendergast, Niall T.
A1 Rivera-Lebron, Belinda
A2 Papadakis, Maxine A.
A2 McPhee, Stephen J.
A2 Rabow, Michael W.
A2 McQuaid, Kenneth R.
SR Print(0)
ID 1186012608
T1 Cystic Fibrosis
T2 Current Medical Diagnosis & Treatment 2022
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269389
LK accessmedicine.mhmedical.com/content.aspx?aid=1186012608
RD 2024/04/25
AB ESSENTIALS  OF  DIAGNOSISPulmonary  disease:  chronic  or  recurrent  productive  cough,  dyspnea,  and  wheezing;  recurrent  airway  infections  or  chronic  colonization  of  the  airways  with  H  influenzae,  P  aeruginosa,  S  aureus,  or  Burkholderia  cenocepacia;  bronchiectasis  and  scarring  on  chest  radiographs;  airflow  obstruction  on  spirometry.Extrapulmonary  disease:  sinus  disease;  gastrointestinal  disease  (pancreatic  insufficiency,  recurrent  pancreatitis,  hepatobiliary  disease,  meconium  ileus,  and  distal  intestinal  obstruction);  genitourinary  problems  (male  infertility  and  urogenital  abnormalities)Sweat  chloride  concentration  >  60  mEq/L  on  two  occasions.Presence  of  two  disease-causing  mutations  in  the  cystic  fibrosis  transmembrane  conductance  regulator  (CFTR)  gene.Abnormal  nasal  potential  difference.