RT Book, Section A1 Duncan, Jacque L. A1 Parikh, Neeti B. A1 Seitzman, Gerami D. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184192530 T1 Principles of Treatment of Ocular Infections T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184192530 RD 2024/03/28 AB Preferably the causative organism is identified before determining treatment of ocular infection, but in most cases, empiric treatment—guided by knowledge of local patterns of microbial resistance—is used in the first instance. In the treatment of conjunctivitis and for prophylaxis against ocular infection, it is preferable to use a drug that is not given systemically. Although fluoroquinolones are advocated for the treatment of conjunctivitis, they are better reserved for treatment of bacterial keratitis and other serious infections. There is no clinical evidence indicating the superiority of any topical antibiotic agent for common bacterial conjunctivitis. Of the available local antibiotics, sodium sulfacetamide is effective and inexpensive. It is available in ointment or solution form. Combined bacitracin-polymyxin ointment is often used prophylactically after corneal foreign body removal for the protection it affords against both gram-positive and gram-negative organisms.