RT Book, Section A1 Shinkai, Kanade A1 Fox, Lindy P. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184190377 T1 Kaposi Sarcoma T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184190377 RD 2024/04/24 AB Human herpes virus 8 (HHV-8), or Kaposi sarcoma–associated herpes virus, is the cause of all forms of Kaposi sarcoma. Kaposi sarcoma occurs in several forms. Classic Kaposi sarcoma occurs in older men, has a chronic clinical course, and is rarely fatal. Endemic Kaposi sarcoma occurs in an often aggressive form in young Black men of equatorial Africa. Iatrogenic Kaposi sarcoma occurs in patients receiving immunosuppressive therapy and improves upon decreasing immunosuppression. Although antiretroviral therapy has reduced the prevalence of HIV-related Kaposi sarcoma, Kaposi sarcoma continues to occur in both well controlled HIV infection or AIDS.