RT Book, Section A1 Shinkai, Kanade A1 Fox, Lindy P. A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184190254 T1 Bullous Pemphigoid T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184190254 RD 2024/04/19 AB Bullous pemphigoid is a relatively benign pruritic disease characterized by tense blisters in flexural areas, usually remitting in 5 or 6 years, with a course characterized by exacerbations and remissions (eFigure 6–77) (eFigure 6–78). Most affected persons are over the age of 60 and men are affected twice as frequently as women. The appearance of blisters may be preceded by pruritic urticarial or edematous lesions for months. Oral lesions are present in one-third. The disease may occur in various forms, including localized, vesicular, vegetating, erythematous, erythrodermic, and nodular. Drugs may induce bullous pemphigoid. The most common offender is furosemide. Immunotherapy for malignancies with PD-1 inhibitors can cause drug-induced bullous pemphigoid.