RT Book, Section A1 Dolan, Brigid A1 Walsh, Judith A2 Papadakis, Maxine A. A2 McPhee, Stephen J. A2 Rabow, Michael W. A2 McQuaid, Kenneth R. SR Print(0) ID 1184155227 T1 Cardiovascular Disease Prevention in Women T2 Current Medical Diagnosis & Treatment 2022 YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269389 LK accessmedicine.mhmedical.com/content.aspx?aid=1184155227 RD 2024/03/29 AB Cardiovascular disease is the leading cause of death in women. Women’s heart disease risk tends to lag about 10 years behind that of men; thus, at any given age, a woman’s baseline risk will be lower than that of a man’s baseline risk. While some heart disease risk factors such as age and family history are not modifiable, other risk factors such as hypertension, hyperlipidemia, smoking, obesity, and diabetes are potentially modifiable. Additionally, sex-specific risk factors may impact a woman’s risk of future heart disease, including adverse pregnancy outcomes (ie, preeclampsia, gestational diabetes, preterm birth, or small for gestational age birth), premature ovarian failure or early menopause, or comorbidities such as autoimmune disease or the sequelae of cancer treatments (ie, chest wall radiation, or trastuzumab or anthracycline treatment for breast cancer). Each of these may be considered a “risk-enhancer” when considering future cardiovascular disease risk.