RT Book, Section A1 Bradbury, Richard S. A2 Boulton, Matthew L. A2 Wallace, Robert B. SR Print(0) ID 1182666009 T1 Hookworm Infection: Necatoriasis and Ancylostomiasis T2 Maxcy-Rosenau-Last Public Health & Preventive Medicine, 16e YR 2022 FD 2022 PB McGraw Hill PP New York, NY SN 9781259644511 LK accessmedicine.mhmedical.com/content.aspx?aid=1182666009 RD 2024/03/28 AB Hookworms are soil-transmitted helminths (STHs) that infect humans in association with poor sanitation in tropical and subtropical climates.1 An estimated 451 million people are infected with hookworms,2 with the highest prevalence in sub-Saharan Africa, South East Asia, and the Pacific.3 The prevalence and intensity of hookworm infection in these populations steadily rises with age and plateaus in adults, although moderate and heavy pediatric hookworm infections are also common.4,5 In areas where overcrowding, poverty, and unsanitary living conditions combined with inadequate healthcare and education prevail, moderate and heavy hookworm infections leading to disease results in enormous human misery and suffering, as well as economic loss. It is estimated that up to 4 million disability adjusted life-years (DALYs) and U.S. $139 billion of productivity are lost annually as a direct result of hookworm disease.6 With this in mind, the World Health Organization (WHO) has established a global target of elimination of morbidity due to STHs (including hookworm), in children in endemic areas by 2020.7