RT Book, Section A1 Hynes, Noreen A. A1 Meyer, Diane A2 Boulton, Matthew L. A2 Wallace, Robert B. SR Print(0) ID 1182674348 T1 Agents of Infection and Principles of Transmission T2 Maxcy-Rosenau-Last Public Health & Preventive Medicine, 16e YR 2022 FD 2022 PB McGraw Hill PP New York, NY SN 9781259644511 LK accessmedicine.mhmedical.com/content.aspx?aid=1182674348 RD 2024/04/19 AB Infectious diseases have posed significant threats to the public’s health for millennia. Despite a change in global and domestic leading causes of morbidity and mortality with a shift to chronic diseases, infectious diseases continue to impose a high burden on individual and population health.1 Therefore, public health practitioners must continue to attend to the prevention and control of infectious diseases. Common infectious diseases challenges in resource rich areas include influenza (which combined with pneumonia is the eighth leading cause of death in the United States), foodborne illnesses, healthcare-associated infections, sexually transmitted diseases, hepatitis C, and human immunodeficiency virus (HIV) infections.2 Although these same infectious diseases abound in lower resource countries, more traditional causes of infectious disease-associated morbidity and mortality prevail in these settings including tuberculosis (TB), malaria, soil-transmitted helminthic (STH) diseases, and diarrheal and acute respiratory infections (particularly in the under-5 age group). Adding to the complexity of the burden of infectious diseases is the identification of new infectious agents or the re-emergence of those in previously endemic areas. Demographic migrations among humans as well as animals, and the vectors and reservoirs of infectious agents, contribute to the introduction of new or the reintroduction of eliminated diseases as population threats where consideration of the classic epidemiological triad of determinants—the human host, the agent, and the human environment—comes into play.3