RT Book, Section
A1 Huppert, Laura A.
A1 Dyster, Timothy G.
SR Print(0)
ID 1189914135
T1 Key Clinical Trials & Publications in General Medicine
T2 Huppert’s Notes: Pathophysiology and Clinical Pearls for Internal Medicine
YR 2021
FD 2021
PB McGraw Hill
PP New York, NY
SN 9781260470079
LK accessmedicine.mhmedical.com/content.aspx?aid=1189914135
RD 2024/09/10
AB SPRINT.N  Eng  J  Med  2015;373(22):2103–2116-  Multicenter,  open-label,  randomized  controlled  trial  that  randomized  patients  at  high  risk  for  CVD  but  who  did  not  have  a  history  of  diabetes  or  stroke  to  an  intensive  (<120  mmHg)  vs.  standard  (<140  mmHg)  SBP  target.  Intensive  BP  control  (target  SBP  <120  mmHg)  improved  CV  outcomes  and  overall  survival  compared  to  the  standard  SBP  goal  <140  mmHg,  with  modest  increase  in  the  risk  of  some  serious  adverse  events.  Similar  benefits  were  demonstrated  in  a  CKD  subgroup  analysis  (JASN  2017:28(9):2561–2563).