RT Book, Section A1 Katzung, Bertram G. A1 Kruidering-Hall, Marieke A1 Tuan, Rupa Lalchandani A1 Vanderah, Todd W. A1 Trevor, Anthony J. SR Print(0) ID 1180556796 T1 Antidepressants T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 13e YR 2021 FD 2021 PB McGraw-Hill Education PP New York, NY SN 9781260117127 LK accessmedicine.mhmedical.com/content.aspx?aid=1180556796 RD 2024/11/04 AB Major depressive disorder (MDD), or endogenous depression, is a depression of mood without any obvious medical or situational causes, manifested by an inability to cope with ordinary events or experience pleasure. The drugs used in MDD are of varied chemical structures; many have effects that enhance the CNS actions of norepinephrine, serotonin, or both.