RT Book, Section
A1 Herrmann, Paul C.
A2 Kaushansky, Kenneth
A2 Prchal, Josef T.
A2 Burns, Linda J.
A2 Lichtman, Marshall A.
A2 Levi, Marcel
A2 Linch, David C.
SR Print(0)
ID 1180482446
T1 Erythrocyte Disorders as a Result of Toxic Agents
T2 Williams Hematology, 10e
YR 2021
FD 2021
PB McGraw-Hill Education
PP New York, NY
SN 9781260464122
LK accessmedicine.mhmedical.com/content.aspx?aid=1180482446
RD 2024/04/18
AB SUMMARYErythrocyte  disorders  can  be  caused  by  a  wide  variety  of  toxic  agents.  Whereas  some  erythrocyte  toxins  damage  red  blood  cells  through  well-defined  mechanisms,  others  have  mechanisms  that  are  incompletely  defined  or  for  which  there  is  complexity  involving  multiple  simultaneous  pathways.  The  well-defined  mechanisms  include  neocytolysis,  damage  from  oxidation,  damage  to  structural  proteins,  damage  to  erythrocyte  membranes,  and  direct  damage  to  metabolic  pathways.  Incompletely  defined  mechanisms  are  responsible  for  toxicity  from  nanoparticles  and  metals  with  broad  biological  activity  spectra  such  as  lead.  A  table  of  other  toxins  not  specifically  described  in  the  text  is  included.