RT Book, Section A1 Radke, Joshua B. A2 Olson, Kent R. A2 Anderson, Ilene B. A2 Benowitz, Neal L. A2 Blanc, Paul D. A2 Clark, Richard F. A2 Kearney, Thomas E. A2 Kim-Katz, Susan Y. A2 Wu, Alan H. B. SR Print(0) ID 1179992661 T1 TETANUS T2 Poisoning & Drug Overdose, 7e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071839792 LK accessmedicine.mhmedical.com/content.aspx?aid=1179992661 RD 2024/04/23 AB Tetanus is a rare disease in developed countries. The incidence of tetanus ranges from 10,000 to 1 million cases per year globally, with only 50–100 of those cases occurring in the United States. Success in prevention of tetanus is largely due to vaccination programs. In developed countries, tetanus is most commonly seen in older persons, recent immigrants, and IV drug users who have not maintained adequate tetanus immunization. Tetanus is caused by an exotoxin produced by Clostridium tetani, an anaerobic, spore-forming, gram-positive rod found widely in soil and in the GI tract.