RT Book, Section
A1 Blanc, Paul D.
A2 Olson, Kent R.
A2 Anderson, Ilene B.
A2 Benowitz, Neal L.
A2 Blanc, Paul D.
A2 Clark, Richard F.
A2 Kearney, Thomas E.
A2 Kim-Katz, Susan Y.
A2 Wu, Alan H. B.
SR Print(0)
ID 1179991839
T1 MANGANESE
T2 Poisoning & Drug Overdose, 7e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9780071839792
LK accessmedicine.mhmedical.com/content.aspx?aid=1179991839
RD 2022/05/24
AB Although  manganese  (Mn)  is  an  essential  trace  nutrient,  intoxication  is  caused  by  chronic  overexposure.  Sources  of  inorganic  manganese  exposure  include  mining,  metal  working,  smelting,  foundries,  and  welding.  There  is  a  potential  link  between  organic  manganese  fungicides  (Maneb  and  Mancozeb)  and  chronic  neurologic  toxicity.  An  organic  manganese  gasoline  additive,  methylcyclopentadienyl  manganese  tricarbonyl  (MMT)  is  in  limited  use  in  the  United  States  and  in  wider  use  elsewhere.  Parenteral  exposure  to  inorganic  manganese  can  occur  through  injection  drug  abuse  of  potassium  permanganate–adulterated  substances,  through  manganese-containing  total  parenteral  nutrition,  and  administration  of  the  manganese-releasing  pharmaceutical  mangafodipir.