RT Book, Section
A1 Blanc, Paul D.
A2 Olson, Kent R.
A2 Anderson, Ilene B.
A2 Benowitz, Neal L.
A2 Blanc, Paul D.
A2 Clark, Richard F.
A2 Kearney, Thomas E.
A2 Kim-Katz, Susan Y.
A2 Wu, Alan H. B.
SR Print(0)
ID 1179991684
T1 ISOCYANATES
T2 Poisoning & Drug Overdose, 7e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9780071839792
LK accessmedicine.mhmedical.com/content.aspx?aid=1179991684
RD 2024/04/16
AB Toluene  diisocyanate  (TDI),  methylene  diisocyanate  (MDI),  hexamethylene  diisocyanate  (HDI),  isophorone  diisocyanate  (IPDI),  and  related  chemicals  are  industrial  components  in  the  polymerization  of  urethane  coatings  and  insulation  materials.  Urethanes  have  widespread  uses  in  sealants,  coatings,  finishes,  glues,  and  even  medical  applications  (eg,  casts).  Most  two-part  urethane  products  contain  some  amount  of  one  of  these  chemicals,  and  lesser  amounts  contaminate  one-part  systems.  Methyl  isocyanate  (the  toxin  released  in  the  disaster  in  Bhopal,  India)  is  a  carbamate  insecticide  precursor;  it  is  not  used  in  urethanes,  has  actions  different  from  those  of  the  TDI  group  of  chemicals,  and  is  not  discussed  here  (see  Table  IV–4).