RT Book, Section
A1 Benowitz, Neal L.
A1 O'Connell, Charles W.
A2 Olson, Kent R.
A2 Anderson, Ilene B.
A2 Benowitz, Neal L.
A2 Blanc, Paul D.
A2 Clark, Richard F.
A2 Kearney, Thomas E.
A2 Kim-Katz, Susan Y.
A2 Wu, Alan H. B.
SR Print(0)
ID 1179991342
T1 ERGOT DERIVATIVES
T2 Poisoning & Drug Overdose, 7e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9780071839792
LK accessmedicine.mhmedical.com/content.aspx?aid=1179991342
RD 2024/04/25
AB Ergot  derivatives  are  used  to  treat  migraine  headache  and  enhance  uterine  contraction  postpartum.  Ergots  are  produced  by  the  fungus  Claviceps  purpurea,  which  may  grow  on  rye  and  other  grains.  Natural  or  synthetic  ergot  drugs  include  ergotamine  (Cafergot,  Ergomar,  Gynergen,  and  Ergostat),  dihydroergotamine  (DHE45),  methysergide  (Sansert),  methylergonovine  (Methergine),  and  ergonovine  (Ergotrate).  Some  ergoloid  derivatives  (dihydroergocornine,  dihydroergocristine,  and  dihydroergocryptine)  have  been  used  in  combination  (Hydergine  and  Deapril-ST)  for  the  treatment  of  dementia.  Bromocriptine  (Parlodel)  and  pergolide  (Permax)  are  ergot  derivatives  with  dopamine  agonist  activity  that  are  used  to  treat  Parkinson  disease.  Bromocriptine  is  also  used  to  treat  hyperprolactinemic  states.