RT Book, Section A1 Rowley, Freda M. A2 Olson, Kent R. A2 Anderson, Ilene B. A2 Benowitz, Neal L. A2 Blanc, Paul D. A2 Clark, Richard F. A2 Kearney, Thomas E. A2 Kim-Katz, Susan Y. A2 Wu, Alan H. B. SR Print(0) ID 1179990524 T1 ANTICONVULSANTS, NEWER T2 Poisoning & Drug Overdose, 7e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071839792 LK accessmedicine.mhmedical.com/content.aspx?aid=1179990524 RD 2022/05/20 AB Developed for the treatment of partial and generalized seizure disorders, these second- and third-generation anticonvulsants are finding wider use in the treatment of chronic and neuropathic pain syndromes; mood disorders, including bipolar and generalized anxiety disorders; and migraine headache prophylaxis. Serious adverse effects with the therapeutic use of ezogabine (retinal pigment abnormalities, blue skin discoloration), felbamate (aplastic anemia, hepatic failure) and vigabatrin (permanent visual field deficits) have led to restrictions in their use.