RT Book, Section A1 O'Connell, Charles W. A2 Olson, Kent R. A2 Anderson, Ilene B. A2 Benowitz, Neal L. A2 Blanc, Paul D. A2 Clark, Richard F. A2 Kearney, Thomas E. A2 Kim-Katz, Susan Y. A2 Wu, Alan H. B. SR Print(0) ID 1179990507 T1 ANTICOAGULANTS, NEWER T2 Poisoning & Drug Overdose, 7e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071839792 LK accessmedicine.mhmedical.com/content.aspx?aid=1179990507 RD 2024/04/24 AB The newer target-specific oral anticoagulant medications dabigatran, rivaroxaban, apixaban, and edoxaban have become increasingly popular alternatives to the vitamin K antagonist, warfarin (see Warfarin and Superwarfarins), the former mainstay of oral anticoagulation for prevention and treatment of venous thrombus events and stroke risk reduction in atrial fibrillation. These newer drugs inhibit a single target-specific step in coagulation rather than blocking multiple vitamin K–dependent blood factors as done by warfarin.