RT Book, Section
A1 Slawski, Barbara
A1 Vasudev, Brahm
A2 Cohn, Steven L.
SR Print(0)
ID 1179531932
T1 Acute Kidney Injury
T2 Decision Making in Perioperative Medicine: Clinical Pearls
YR 2021
FD 2021
PB McGraw Hill
PP New York, NY
SN 9781260468106
LK accessmedicine.mhmedical.com/content.aspx?aid=1179531932
RD 2024/04/25
AB Acute  kidney  injury  (AKI)  is  defined  as  an  acute  and  potentially  reversible  decline  in  the  kidney  function/glomerular  filtration  rate  (GFR)  that  occurs  over  hours  to  days.  It  represents  a  spectrum  of  kidney  injury  ranging  from  mild  to  more  severe  forms  of  injury  requiring  renal  replacement  therapy  (RRT).  While  AKI  can  occur  in  patients  with  normal  kidney  function,  patients  with  a  history  of  chronic  kidney  disease  (CKD)  are  at  higher  risk  (AKI  on  CKD).  The  Kidney  Disease:  Improving  Global  Outcomes  (KDIGO)  criteria  are  now  accepted  worldwide  as  the  criteria  for  defining  AKI  (Table  40-1).1  Although  AKI  is  more  common  after  cardiac  surgery,  its  incidence  after  noncardiac  surgery  is  high  as  well.  Even  small  postoperative  increases  in  creatinine  are  associated  with  several  adverse  outcomes  including  higher  rates  of  morbidity,  mortality,  cardiovascular  events,  longer  lengths  of  stay,  cost,  and  poor  surgical  outcomes.