RT Book, Section A1 Katzung, Bertram G. A1 Kruidering-Hall, Marieke A1 Trevor, Anthony J. SR Print(0) ID 1179221470 T1 Agents Used in Cytopenias; Hematopoietic Growth Factors T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 12e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259641022 LK accessmedicine.mhmedical.com/content.aspx?aid=1179221470 RD 2024/03/28 AB Blood cells play essential roles in oxygenation of tissues, coagulation, protection against infectious agents, and tissue repair. Blood cell deficiency is a relatively common occurrence that can have profound repercussions. Anemia, a deficiency in oxygen-carrying erythrocytes, is either classified as microcytic, due to an insufficient supply of iron, or macrocytic often due to a deficiency of either vitamin B12 or folic acid. Pharmacologic treatment of these types of anemia usually involves replacement of the missing substance. An alternative therapy for certain types of anemia and for deficiency in other types of blood cells is administration of recombinant hematopoietic growth factors, which stimulate the production of various lineages of blood cells and regulate blood cell function.