RT Book, Section
A1 Katzung, Bertram G.
A1 Kruidering-Hall, Marieke
A1 Trevor, Anthony J.
SR Print(0)
ID 1179218676
T1 Introduction to CNS Pharmacology
T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 12e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259641022
LK accessmedicine.mhmedical.com/content.aspx?aid=1179218676
RD 2024/04/16
AB Drugs  that  act  on  the  central  nervous  system  (CNS)  are  the  most  commonly  prescribed  drugs  in  current  use.  Most  of  these  drugs  act  by  changing  ion  flow  through  transmembrane  channels  of  nerve  cells.  Transmitter  reuptake  transporters  constitute  a  second  class  of  drug  targets,  especially  for  antidepressant  agents.  Inhibition  of  acetylcholine  metabolism  is  the  major  action  of  the  drugs  currently  approved  for  use  in  Alzheimer’s  disease  and  GABA  metabolism  is  inhibited  by  an  anticonvulsant  agent.  Finally,  a  few  drugs  appear  to  act  by  altering  the  function  of  neuroglia;  these  satellite  cells  support  neurons  metabolically  and  may  also  modulate  transmitter  synthesis  and  disposition.