RT Book, Section
A1 Yokose, Chio
A1 Choi, Hyon K.
A2 Stone, John H.
SR Print(0)
ID 1180198057
T1 Gout
T2 Current Diagnosis & Treatment: Rheumatology, 4e
YR 2021
FD 2021
PB McGraw Hill
PP New York, NY
SN 9781259644641
LK accessmedicine.mhmedical.com/content.aspx?aid=1180198057
RD 2024/04/25
AB Caused  by  deposition  of  monosodium  urate  crystals  due  to  longstanding  hyperuricemia.Usually  begins  as  an  intermittent,  acute  mono-  or  oligoarthritis,  especially  of  the  first  metatarsophalangeal  joint.Flares  typically  become  more  frequent  and  involve  more  joints  over  time,  in  the  absence  of  treatment.Diagnosed  by  evaluating  joint  fluid  for  monosodium  urate  crystals  using  polarized  light  microscopy.Extra-articular  manifestations  include  subcutaneous  tophi  and  renal  stones.Flares  of  arthritis  respond  to  anti-inflammatory  drugs  such  as  nonsteroidal  anti-inflammatory  drugs,  colchicine,  or  glucocorticoids.