RT Book, Section A1 Morgan, Nadia D. A1 Wigley, Fredrick M. A2 Stone, John H. SR Print(0) ID 1180196752 T1 Raynaud Phenomenon T2 Current Diagnosis & Treatment: Rheumatology, 4e YR 2021 FD 2021 PB McGraw Hill PP New York, NY SN 9781259644641 LK accessmedicine.mhmedical.com/content.aspx?aid=1180196752 RD 2024/04/18 AB Raynaud phenomenon (RP) is an exaggeration of the normal vasospastic reaction to cold environments or emotional stress*.Characterized by well-demarcated color changes (pallor, cyanosis, hyperemia) involving the peripheral digits (fingers and toes).Classified clinically into primary or secondary forms.Primary RP is idiopathic and functional in nature, the integrity of the blood vessel architecture is preserved.Secondary RP is associated with an underlying structural vasculopathy and may be complicated by digital ischemia, recurrent digital ulcerations, rapid deep tissue necrosis, and amputation.The principal approach in the management of RP entails preventative measures through the avoidance of cold environments and use of protective clothing to maintain adequately warm core and peripheral body temperatures.Therapeutic agents are indicated if quality of life is affected adversely or if there are complications of tissue ischemia, including digital ulcers.