RT Book, Section A1 Dall’Era, Maria A2 Stone, John H. SR Print(0) ID 1180196547 T1 Systemic Lupus Erythematosus T2 Current Diagnosis & Treatment: Rheumatology, 4e YR 2021 FD 2021 PB McGraw Hill PP New York, NY SN 9781259644641 LK accessmedicine.mhmedical.com/content.aspx?aid=1180196547 RD 2024/04/24 AB Predilection for females of childbearing age.Multisystem disease that has a tendency to remit and relapse.Photosensitive rash, polyarthritis, serositis, and fatigue are common flare manifestations.Renal disease, central nervous system involvement, and complications of antiphospholipid antibodies can cause major morbidity.Treatment-related morbidity, particularly from glucocorticoids, constitutes a major source of damage associated with having lupus.Presence of antinuclear antibodies.Certain autoantibodies (anti-dsDNA and anti-Sm) have great specificity for the diagnosis of systemic lupus erythematosus (SLE) but lack sensitivity.Hypocomplementemia may occur during flares.