RT Book, Section A1 Chrousos, George P. A2 Katzung, Bertram G. A2 Vanderah, Todd W. SR Print(0) ID 1176975357 T1 Adrenocorticosteroids & Adrenocortical Antagonists T2 Basic & Clinical Pharmacology, 15e YR 2021 FD 2021 PB McGraw-Hill PP New York, NY SN 9781260452310 LK accessmedicine.mhmedical.com/content.aspx?aid=1176975357 RD 2024/03/28 AB CASE STUDYA 19-year-old man complains of anorexia, fatigue, dizziness, and weight loss of 8 months’ duration. The examining physician discovers postural hypotension and moderate vitiligo (depigmented areas of skin) and obtains routine blood tests. She finds hyponatremia, hyperkalemia, and acidosis and suspects Addison disease. She performs a standard ACTH 1–24 stimulation test, which reveals an insufficient plasma cortisol response, which is compatible with primary adrenal insufficiency. The diagnosis of autoimmune Addison disease is made, and the patient must start replacement of the hormones he cannot produce himself. How should this patient be treated? What precautions should he take?