RT Book, Section
A1 Williams, Saralyn R.
A1 Thurman, R. Jason
A2 Knoop, Kevin J.
A2 Stack, Lawrence B.
A2 Storrow, Alan B.
A2 Thurman, R. Jason
SR Print(0)
ID 1181057117
T1 Cardiac Glycoside Plant Ingestion
T2 The Atlas of Emergency Medicine, 5e
YR 2021
FD 2021
PB McGraw-Hill
PP New York, NY
SN 9781260134940
LK accessmedicine.mhmedical.com/content.aspx?aid=1181057117
RD 2024/04/18
AB Cardiac  glycosides  (CGs)  are  found  in  the  leaves,  flowers,  and  seeds  of  Nerium  oleander  (common  oleander),  Thevetia  peruviana  (yellow  oleander),  Digitalis  purpurea  (foxglove),  Strophanthus  gratus  (ouabain),  Convallaria  majalis  (lily  of  the  valley),  Apocynum  cannabinum  (dogbane),  Urginea  maritima  and  Urginea  indica  (squill),  and  Cheiranthus  cheiri  (wallflower).  If  ingested,  they  produce  clinical  findings  similar  to  digoxin  toxicity.  The  drinking  of  foxglove  and  oleander  tea  may  be  a  cause  of  CG  toxicity.  Therapeutic  effects  occur  from  inhibition  of  the  cardiac  cell  membrane  sodium-potassium  ATP  pump,  resulting  in  increased  automaticity,  decreased  conduction  through  the  atrioventricular  node,  and  improved  inotropy.