RT Book, Section A1 Hardin, J. Matthew A2 Knoop, Kevin J. A2 Stack, Lawrence B. A2 Storrow, Alan B. A2 Thurman, R. Jason SR Print(0) ID 1181043770 T1 Drug Eruptions T2 The Atlas of Emergency Medicine, 5e YR 2021 FD 2021 PB McGraw-Hill PP New York, NY SN 9781260134940 LK accessmedicine.mhmedical.com/content.aspx?aid=1181043770 RD 2024/03/29 AB Exanthematous drug eruptions present 7 to 14 days after a new medication but may appear sooner if the patient is rechallenged with the culprit medication. A symmetric, erythematous, macular and papular eruption is most frequently encountered. Typically, pruritus and low-grade fever are present. The macules and papules usually become confluent and may progress to an exfoliative dermatitis (rarely to erythroderma). The eruption is progressive over the first few days and, if the culprit medication is stopped, completely resolves over 7 to 14 days.