RT Book, Section
A1 Hardin, J. Matthew
A2 Knoop, Kevin J.
A2 Stack, Lawrence B.
A2 Storrow, Alan B.
A2 Thurman, R. Jason
SR Print(0)
ID 1181043760
T1 Erythema Multiforme
T2 The Atlas of Emergency Medicine, 5e
YR 2021
FD 2021
PB McGraw-Hill
PP New York, NY
SN 9781260134940
LK accessmedicine.mhmedical.com/content.aspx?aid=1181043760
RD 2024/04/20
AB Erythema  multiforme  (EM)  begins  with  symmetric,  erythematous,  sharply  defined  extremity  or  trunk  macules,  and  evolves  into  a  “targetoid”  or  “bull’s  eye”  morphology  (a  flat,  dusky,  central  area  with  two  concentric,  erythematous  rings).  Bullae  may  appear  in  the  central  dusky  area  (bullous  EM).  The  mucous  membranes,  typically  oral,  may  become  involved  and,  when  severe,  raise  concern  for  SJS.  The  typical  targetoid  lesions  allow  a  diagnosis  to  be  made  clinically  (bullae,  purpura,  and  mucosal  involvement  should  prompt  a  dermatology  consultation).  The  rash  usually  persists  for  1  to  4  weeks.