RT Book, Section
A1 Zafren, Ken
A1 Thurman, R. Jason
A1 Jones, Ian D.
A2 Knoop, Kevin J.
A2 Stack, Lawrence B.
A2 Storrow, Alan B.
A2 Thurman, R. Jason
SR Print(0)
ID 1181050805
T1 High-Altitude Cerebral Edema
T2 The Atlas of Emergency Medicine, 5e
YR 2021
FD 2021
PB McGraw-Hill
PP New York, NY
SN 9781260134940
LK accessmedicine.mhmedical.com/content.aspx?aid=1181050805
RD 2024/04/19
AB Acute  mountain  sickness  (AMS)  is  a  symptom  complex  that  usually  begins  12  to  24  hours  after  ascent  to  high  altitude  and  consists  of  headache  and  one  or  more  other  symptoms,  including  gastrointestinal  symptoms,  fatigue  and/or  weakness,  dizziness  and/or  lightheadedness,  and  difficulty  sleeping.  High-altitude  cerebral  edema  (HACE)  is  a  severe  form  of  AMS,  clinically  defined  by  the  presence  of  acute  truncal  ataxia,  altered  mental  status,  or  both.  Usually  this  occurs  as  a  progression  from  AMS  to  HACE,  but  HACE  may  occur  without  antecedent  AMS.  If  not  effectively  treated,  HACE  may  progress  to  coma  or  death.  Focal  neurologic  findings  other  than  truncal  ataxia  are  rare  and  should  suggest  another  diagnosis,  such  as  acute  stroke  or  venous  sinus  thrombosis.